Q2 2026 13F · SEC CIK 1832749
72 Investment Holdings, LLC
Investment managerFiled 2026-08-14 for Q2 2026. Open the filing ↗ · All SEC filings ↗
- Reported 13F value
- $50.0M
- Reported positions
- 5
- Top holdings a year, 3 yrs
- -6.9%
- Average holding period
- 2.6 yrs
72 Investment Holdings, LLC is an investment manager that reported 5 positions worth $50.0M in its Q2 2026 13F, filed 2026-08-14. Its largest holdings were Praxis Precision Medicines I (PRAX, 44.2%), Alto Neuroscience Inc (ANRO, 35.3%), Lenz Therapeutics Inc (LENZ, 11.6%). A portfolio copying its top holdings returned -6.9% a year over the last 3 years, against 21.8% for the S&P 500.
72 Investment Holdings, LLC holdings all 5 positions.
Weights are shares of the filer's total reported 13F value, compared with Q1 2026. Share changes may reflect splits; weight changes also reflect price moves. A 13F shows long US-listed positions only, up to 135 days after the fact.
| Stock | % of 13F value | Share change | Reported value |
|---|---|---|---|
| PRAXPraxis Precision Medicines I | 44.2% | +0.0% | $22.1M |
| ANROAlto Neuroscience Inc | 35.3% | +0.0% | $17.6M |
| LENZLenz Therapeutics Inc | 11.6% | +0.0% | $5.8M |
| KRROKorro Bio Inc | 7.3% | +0.0% | $3.6M |
| CRBUCaribou Biosciences Inc | 1.7% | +0.0% | $834K |
What 72 Investment Holdings, LLC bought and sold in Q2 2026, against Q1 2026.
New positions
No new positions among the largest holdings.
Added to
No position grew by more than 5%.
Reduced
No position shrank by more than 5%.
Sold out
Nothing sold out.
Share counts compared with the Q1 2026 13F; a split also changes share counts.
How the holdings did against the S&P 500.
- 1 year
- -29.4% /yr
- S&P 500 +20.1%
- 3 years
- -6.9% /yr
- S&P 500 +21.8%
- 5 years
- +27.7% /yr
- S&P 500 +13.4%
A portfolio of the filer's 20 largest 13F positions, weighted by value and rebuilt each quarter on the day the filing became public. 13Fs show long US-listed positions only, so this is an estimate of the stock picks, not the fund's reported returns.
Reported 13F value by quarter.
| Quarter | 13F value | Positions |
|---|---|---|
| Q2 2026 | $50.0M | 5 |
| Q1 2026 | $49.6M | 5 |
| Q4 2025 | $50.6M | 5 |
| Q3 2025 | $67.9M | 5 |
| Q2 2025 | $38.3M | 6 |
| Q1 2025 | $35.6M | 6 |
| Q4 2024 | $49.1M | 7 |
| Q3 2024 | $46.5M | 7 |
| Q2 2024 | $39.8M | 7 |
| Q1 2024 | $67.1M | 7 |
| Q4 2023 | $22.5M | 6 |
| Q3 2023 | $14.9M | 5 |
Questions about 72 Investment Holdings, LLC's portfolio
What stocks does 72 Investment Holdings, LLC own?
72 Investment Holdings, LLC's latest 13F, for Q2 2026 and filed Aug 14, 2026, lists 5 positions worth $50.0M. The largest are Praxis Precision Medicines I (PRAX) at 44.2%, Alto Neuroscience Inc (ANRO) at 35.3%, Lenz Therapeutics Inc (LENZ) at 11.6%, Korro Bio Inc (KRRO) at 7.3% and Caribou Biosciences Inc (CRBU) at 1.7%.
What did 72 Investment Holdings, LLC buy last quarter?
72 Investment Holdings, LLC opened no new positions and grew none by more than 5% among its largest holdings in Q2 2026.
What did 72 Investment Holdings, LLC sell last quarter?
72 Investment Holdings, LLC sold out of nothing and cut no large position by more than 5% in Q2 2026.
How has 72 Investment Holdings, LLC's portfolio performed?
A portfolio copying 72 Investment Holdings, LLC's 20 largest 13F holdings each quarter, from the day each filing was public, returned -6.9% a year over the last 3 years, against +21.8% for the S&P 500. Over 1 year: -29.4% against +20.1%. Over 5 years: +27.7% a year against +13.4%.
When is 72 Investment Holdings, LLC's next 13F filing due?
13F filings are due 45 days after each quarter ends. 72 Investment Holdings, LLC's filing for the quarter ending Sep 30, 2026 is due by Nov 14, 2026; this page updates the day after it is published.