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AGIO · Insider trading · 13F holders · Congress trades

Agios Pharmaceuticals, Inc. (AGIO)

Who is buying and selling AGIO: company insiders on SEC Form 4, hedge funds and superinvestors on Form 13F, and members of Congress under the STOCK Act. Every figure links to the filing or page it comes from.

13F filers holding
15
Insider buys, 90 days
$0
Insider sales, 90 days
$1.3M
Congress trades, 12 months
3

AGIO at a glance

  • Between Aug 1, 2026 and Oct 29, 2026, 1 AGIO insider filed 3 sales worth $1.3M on SEC Form 4, and no open-market purchases; 3 of the sales were pre-planned under Rule 10b5-1.
  • 15 13F filers hold AGIO among their 50 largest positions, worth $688.9M combined. The biggest bets by portfolio weight are Lynx1 Capital Management LP (14.6%), Foresite Capital Management VI LLC (4.5%) and Ishara Investments LP (4.5%). In their latest 13Fs, 2 managers opened a new position and 4 added to one.
  • Members of Congress have disclosed 8 AGIO trades since 2015, 3 purchases and 0 sales in the past year; the latest was Gilbert Ray Cisneros, Jr. (D-CA), buying $1K–15K on Aug 20, 2026.
  • AGIO last closed at $37.23 on Oct 29, 2026.

AGIO insider trading

Between Aug 1, 2026 and Oct 29, 2026, 1 AGIO insider filed 3 sales worth $1.3M on SEC Form 4, and no open-market purchases; 3 of the sales were pre-planned under Rule 10b5-1.

AGIO insider purchases and sales
FiledInsiderRoleTradeSharesPriceValueForm 4
Oct 28, 2026Gheuens SarahChief Medical OfficerSale10b5-17,866$37.69$296KSEC
Oct 23, 2026Gheuens SarahChief Medical OfficerSale10b5-11,989$37.53$75KSEC
Aug 6, 2026Gheuens SarahChief Medical OfficerSale10b5-130,000$30.48$914KSEC

Every AGIO insider and Form 4 filing →

Who owns AGIO? Hedge funds and superinvestors

15 13F filers hold AGIO among their 50 largest positions, worth $688.9M combined. The biggest bets by portfolio weight are Lynx1 Capital Management LP (14.6%), Foresite Capital Management VI LLC (4.5%) and Ishara Investments LP (4.5%). In their latest 13Fs, 2 managers opened a new position and 4 added to one.

13F filers holding AGIO
Manager% of portfolioValueSharesLast quarter13F
Farallon Capital Management, L.l.c.Hedge fund1.3%$219.6M5,917,400+4.1% sharesQ2 2026
Lynx1 Capital Management LPHedge fund14.6%$126.5M3,408,937+30.5% sharesQ2 2026
Armistice Capital, LLCHedge fund2.5%$89.1M2,400,000-11.6% sharesQ2 2026
Erste Asset Management GmbHAsset manager0.6%$82.0M2,154,900-20.3% sharesQ2 2026
ADAR1 Capital Management, LLCHedge fund2.3%$47.8M1,288,053—Q2 2026
Foresite Capital Management VI LLCHedge fund4.5%$29.1M785,000+49.5% sharesQ2 2026
Parkman Healthcare Partners LLCHedge fund2.5%$24.8M669,046+65.8% sharesQ2 2026
Defilade Capital Management, L.P.Hedge fund2.7%$20.3M546,848NewQ2 2026
Rock Springs Capital Management LPHedge fund1.0%$19.8M532,563-33.4% sharesQ2 2026
Palo Alto Investors LPHedge fund1.1%$7.9M213,601+0.0% sharesQ2 2026
Tetragon Partners GP LtdHedge fund1.2%$7.6M205,579+24.7% sharesQ2 2026
Ishara Investments LPHedge fund4.5%$6.1M164,000NewQ2 2026
Knott David M JrInvestment manager1.9%$3.5M95,058+2.1% sharesQ2 2026
Exome Asset Management LLCHedge fund1.6%$2.6M70,500-43.6% sharesQ2 2026
Seven Fleet Capital Management LPHedge fund0.3%$2.1M56,900-72.8% sharesQ2 2026

Each manager counts with its latest 13F (Q2 2026: 15). Screen AGIO in the grand portfolio →

AGIO stock trades by members of Congress

Members of Congress have disclosed 8 AGIO trades since 2015, 3 purchases and 0 sales in the past year; the latest was Gilbert Ray Cisneros, Jr. (D-CA), buying $1K–15K on Aug 20, 2026.

Congress trades in AGIO
FiledMemberTradeAmountTradedSince
Sep 10, 2026Gilbert Ray Cisneros, Jr.D-CA · HouseBuy$1K–15KAug 20, 2026-8.8%
Apr 7, 2026Gilbert Ray Cisneros, Jr.D-CA · HouseBuy$1K–15KMar 3, 2026+7.7%
Jan 12, 2026Gilbert Ray Cisneros, Jr.D-CA · HouseBuy$1K–15KDec 11, 2025+11.7%
May 6, 2025Gilbert Ray Cisneros, Jr.D-CA · HouseBuy$1K–15KApr 17, 2025+10.9%
Feb 11, 2025Gilbert Ray Cisneros, Jr.D-CA · HouseBuy$1K–15KJan 29, 2025-9.1%
Feb 15, 2024Josh GottheimerD-NJ · HouseBuy$1K–15KJan 24, 2024+42.6%
Jun 7, 2015Thomas MacArthurR-NJ · HouseSale$1K–15KMay 27, 2015-75.1%
Apr 11, 2015Thomas MacArthurR-NJ · HouseBuy$1K–15KMar 18, 2015-71.1%

3 members have traded AGIO: Gilbert Ray Cisneros, Jr., Josh Gottheimer, Thomas MacArthur.

Analysis mentioning AGIO

Posts from the blog that cover Agios Pharmaceuticals, Inc., newest first.

AGIO questions and answers

Are insiders buying AGIO stock?

Between Aug 1, 2026 and Oct 29, 2026, 1 AGIO insider filed 3 sales worth $1.3M on SEC Form 4, and no open-market purchases; 3 of the sales were pre-planned under Rule 10b5-1.

Which hedge funds own AGIO?

15 13F filers hold AGIO among their 50 largest positions, worth $688.9M combined. The biggest bets by portfolio weight are Lynx1 Capital Management LP (14.6%), Foresite Capital Management VI LLC (4.5%) and Ishara Investments LP (4.5%). In their latest 13Fs, 2 managers opened a new position and 4 added to one.

Has Congress traded AGIO?

Members of Congress have disclosed 8 AGIO trades since 2015, 3 purchases and 0 sales in the past year; the latest was Gilbert Ray Cisneros, Jr. (D-CA), buying $1K–15K on Aug 20, 2026.

Who is the largest holder of AGIO?

Among 13F filers, Farallon Capital Management, L.l.c. reports the largest AGIO position, $219.6M (5,917,400 shares) in its Q2 2026 13F. The biggest bet by portfolio weight is Lynx1 Capital Management LP's: 14.6% of its portfolio.

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